Selecting the Right Knife for Cutting Paraffin Embedded Sections

Which knife is recommended for cutting paraffin embedded sections on a rotary microtome?

1) Disposable knife

2) Steel knife

3) Tungsten carbide knife

4) Diamond knife

Final answer: Option 1

Answer:

In cutting paraffin embedded sections on a rotary microtome, the recommended knife is a disposable knife.

When cutting paraffin embedded sections on a rotary microtome, the recommended knife to use is a disposable knife. Different knives have specific applications and the disposable knife is preferred for this procedure due to its sharp and precise cut, as well as its cost-effectiveness.

Although steel and tungsten carbide knives can also be used, they require honing and extra care that can make the process more time-consuming and challenging. The diamond knife is usually reserved for extremely thin cuts (ultramicrotomy) and is not typically used with paraffin embedded sections.